The midfielder heads to the One Call Stadium after terms were agreed on a standard season-long loan with the Stags.
Stirk, 20, was a standout performer for the Under-23s last term as they went on to win the Professional Development League national title.
He also stepped up to Lee Bowyer's team at the conclusion of the 2020/21 season, making his senior debut against Cardiff City in the Sky Bet Championship before backing up this composed performance in another start at Blackburn Rovers on the final day.
He will now link up with Nigel Clough's side ahead of their League Two campaign to continue his development and secure further experience in the professional game.
Good luck, Ryan!